- Creamino® or Guanidinoacetic acid (GAA) is the direct endogenous precursor of creatine in all vertebrates.
- The body can produce GAA from the amino acids, glycine and arginine or it can be provided via feed as Creamino®.
- Creatine is a naturally occurring component in the body tissue of animals and is a critical component in energy metabolism.
- In contrast to other nutrients, creatine is stored in the muscle and directly reloads ATP for energy supply to the muscle. This is particularly important during periods of high energy demand and prevents formation of reactive oxygen substances which have a negative effect on performance.
- Therefore, creatine is of primary importance in places with high energy need, such as skeletal muscle, heart, brain, sperm and immune cells.
- Despite its importance, it is estimated that only 66% of the daily creatine requirement can be synthesised by the animal with the remaining requirement provided from the diet.
- While creatine is a natural constituent in meat or fish, creatine does not readily withstand heat treatment during rendering placing further pressure on creatine supply. In vegetarian rations, creatine supply is further reduced, and this deficit of creatine may reduce performance accordingly.
- In muscle, creatinine is formed from creatine. This constant loss of creatine is proportional to muscle mass and must be replaced by resynthesis of creatine. Without constant replacement of creatine muscle mass is reduced.
An extensive number of controlled research trials and field trials have proven that Creamino® in feed:
- Lifts ME (50-100 kcal) in pigs
- Increases creatine concentration in tissues (all species)
- Improves water holding capacity and meat quality in pigs
- Improves daily weight gain and FCR in pigs
- Increases survival of low birth weight piglets
For Further Information – please click below:
Creatine in Animal Feeds – 10 Key Facts